Central Missouri Vacations from $521
Book a Hotel + Flight or Car together to unlock savings
Your Central Missouri Vacation
Whether you plan to visit Central Missouri for its rural countryside, spectacular views or something else entirely, this is one destination you'll never forget. Create your ultimate getaway with one of our Central Missouri vacation packages. With so much to see on a trip to Central Missouri, it can be tricky to know where to start. Kick off your journey in Columbia at Mizzou Arena and Columbia Mall — two much-loved attractions here. Another top city worth adding to your itinerary is Osage Beach. Don't miss Bagnell Dam and Lake of the Ozarks and Bagnell Dam Viewpoint. Find some travel buddies and start packing, because your Central Missouri vacation is only a few clicks away with Expedia.
The Latest Central Missouri vacation packages
Price found within the past 48 hours. Click for updated prices.
Capital O Amerihost Inn and Suites Mexico Hwy 54 MO
Price was $585, price is now $521 per person
$521
per person
Dec 29 - Jan 2
found 6 hours ago
Roundtrip non-stop flight included
San Antonio (SAT) to Columbia (COU)
11.2/10 Exceptional! (381 reviews)
Staff were very friendly and accommodating. Room was very clean and comfortable!
Reviewed on Nov 11, 2025
Capital O Amerihost Inn and Suites Fulton Hwy 54 MO
Price was $605, price is now $530 per person
$530
per person
Dec 29 - Jan 2
found 6 hours ago
Roundtrip non-stop flight included
San Antonio (SAT) to Columbia (COU)
11.2/10 Exceptional! (456 reviews)
The clerk was able to provide another room when th one I originally booked was not available, simple and easy. Room was clean, smoke free, and stocked well. An enjoyable experience, and would consider it in the future.
Reviewed on Oct 13, 2025
Capital O Amerihost Inn and Suites Kingdom City Hwy 54 MO
Price was $601, price is now $531 per person
$531
per person
Dec 29 - Jan 2
found 6 hours ago
Roundtrip non-stop flight included
San Antonio (SAT) to Columbia (COU)
13.6/10 Exceptional! (335 reviews)
Didn’t use the Air-conditioning, Did not shop
Reviewed on Nov 15, 2025
Baymont by Wyndham Kingdom City
Price was $657, price is now $591 per person
$591
per person
Dec 29 - Jan 2
found 6 hours ago
Roundtrip non-stop flight included
San Antonio (SAT) to Columbia (COU)
16.4/10 Exceptional! (128 reviews)
This is a basic hotel. Spotless clean with freshly renovated rooms. Pretty much the only 2 star hotel that I would stay in. Definitely stop here when traveling. Or going to 54 Ciuntry
Reviewed on Nov 15, 2025
Days Inn by Wyndham Mexico
Price was $628, price is now $570 per person
$570
per person
Dec 29 - Jan 2
found 6 hours ago
Roundtrip non-stop flight included
San Antonio (SAT) to Columbia (COU)
13.6/10 Exceptional! (294 reviews)
It was adequate. Didn’t like the noisy bathroom fan which was connected to light. Couldn’t turn it off without turning out light. Breakfast was basic.
Reviewed on Oct 12, 2025
Don't see what you're looking for?
See all available trips from Columbus to Central Missouri
View all tripsWhere to stay in Central Missouri
Find the best Central Missouri areas and neighborhoods for the activities you enjoy most. Learn more about Central Missouri
Shawnee Bend
While Shawnee Bend isn't home to many top sights, Sycamore Creek Golf Club and Osage Beach Premium Outlets are some notable places to visit nearby.
Discover the most popular places to visit in Central Missouri
University of Missouri
4.5/5(449 reviews)
Take a tour of the stunning botanical gardens interspersed with the eclectic range of neo-Gothic and redbrick structures in this historic university.
Ha Ha Tonka State Park
4.5/5(102 reviews)
This state park at the top of a bluff features evocative castle ruins, as well as caves, a natural bridge, sinkholes and a scenic lake.
Missouri State Capitol
4/5(85 reviews)
Ascend to the dome for a wonderful vista and browse the range of fascinating public art in this important state building.
What to do in Central Missouri
St. Louis Ghost Tour: Sinister Sins & Shadows
$26
per adult
St. Louis Premium Driving Tour with Boat Ride & Arch
$174
per adult
100% of travellers recommend
St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour
$32
per adult
100% of travellers recommend
Central Missouri Hotel Deals
Wyndham Executive Center Columbia
2200 I-70 Drive SW Columbia MO
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $105 total per night from Nov 30 to Dec 1
$105 total
Nov 30 - Dec 1
Total with taxes and fees
8.2/10 Very Good! (1,000 reviews)
Room was spotless. Staff was good. Breakfast was nice , and the breakfast host was outstanding 💕
Reviewed on Nov 7, 2025
Country Inn & Suites by Radisson, Columbia, MO
817 N Keene St Columbia MO
Fully refundable
$83 nightly
The price is $93 total per night from Dec 11 to Dec 12
$93 total
Dec 11 - Dec 12
Total with taxes and fees
9/10 Wonderful! (1,667 reviews)
Clean room quiet and very friendly staff
Reviewed on Nov 12, 2025
Baymont by Wyndham Columbia, MO
2500 I 70 Dr Sw Columbia MO
Fully refundableReserve now, pay when you stay
$61 nightly
The price is $69 total per night from Nov 23 to Nov 24
$69 total
Nov 23 - Nov 24
Total with taxes and fees
8/10 Very Good! (584 reviews)
The gravey is terrible. Everything. Else. Is good..
Reviewed on Nov 15, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Central Missouri Vacation Packages
Central Missouri Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Columbia Regional Airport (COU) |
More vacations you might like
Explore a world of travel with Expedia
- Lohman Hotels
- Motels in Lohman
- St. Martins Hotels
- Russellville Hotels
- Centertown Hotels
- Hotels near Runge Nature Center
- Cabin Rentals in Missouri
- Jefferson City Hotels
- Hartsburg Hotels
- 4 Star Hotels in Hartsburg
- Motels in Hartsburg
- 5 Star Hotels in Hartsburg
- Non-Smoking Hotels in Hartsburg
- Hotels & Resorts for Couples in Hartsburg
- 3 Star Hotels in Hartsburg
- Farmstay in Hartsburg
- Hotels near Oak Hills Golf Center
- All-inclusive Resorts in Missouri
- California Hotels
- Vacation Homes in California
- Motels in California
- Hotels with Free Parking in California
- Cabin Rentals in California
- Cottages in California
- 5 Star Hotels in California
- Apartments in California
- Pet-friendly Hotels in California
- Moniteau County Hotels
- Family Hotels in Missouri
- Resorts & Hotels with Spas in Missouri
- Missouri Hotels
- Casino Hotels in Missouri
- Cheap Hotels in Jefferson City
- Hotels near Moniteau County Courthouse
- Adults Only Resorts & in Missouri
- Pet-friendly Hotels in Jefferson City
- B&B in Jefferson City
- 5 Star Hotels in Jefferson City
- Luxury Hotels in Jefferson City
- Hotels with an Indoor Pool in Jefferson City
- Hotels near Miller Performing Arts Center
- Hotels on the Lake in Missouri
- Apartments in Jefferson City
- Hotels with an Outdoor Pool in Jefferson City
- Cabin Rentals in Jefferson City
- Resorts & Hotels with Spas in Jefferson City
- Hotels with Hot Tubs in Jefferson City
- Hotels with Bars in Jefferson City
- Historic Hotels in Jefferson City
- Visit Lohman
- Runge Nature Center
- Oak Hills Golf Center
- Visit Hartsburg
- California Vacations
- Missouri Vacations
- Missouri State Capitol
- Moniteau County Courthouse
- Miller Performing Arts Center
- Jefferson City Vacations
- Visit Mcgirk
- The Missouri Governor ́s Mansion
- Lincoln University of Missouri
- Visit Missouri
- Visit Jefferson City
- Car rentals near St. Martins
- Car rentals near Apache Flats
- Car rentals near Hartsburg
- Hertz Rental Cars in California
- Alamo Rent A Car Rental Cars in California
- National Car Rental Rental Cars in California
- Thrifty Car Rental Rental Cars in California
- Payless Rental Cars in California
- Sixt Rental Cars in California
- Avis Rental Cars in California
- Car rentals near California
- Airport Van Rental Rental Cars in California
- Budget Rental Cars in California
- Apex Car Rentals Rental Cars in California
- Convertible Car Rentals in California
- Enterprise Rental Cars in California
- Car rentals near Jefferson City
- Car rentals near Mcgirk
- Car rentals near Missouri
- Enterprise Rental Cars in Jefferson City
- Budget Rental Cars in Jefferson City
- Hertz Rental Cars in Jefferson City
- Avis Rental Cars in Jefferson City
- Van Car Rentals in Jefferson City
- Van Car Rentals in Missouri
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.